Contractile properties of lower leg muscles are normal in Parkinson's disease.

نویسندگان

  • A Hufschmidt
  • K Stark
  • C H Lücking
چکیده

Contraction parameters (time-to-peak and half relaxation time), responses to short tetani and resistance to stretch were studied in the lower leg muscles of Parkinsonian patients and in age-matched controls. It was possible to distinguish between muscle groups of different fibre type composition in normal subjects on the basis of their contraction and relaxation velocities. These parameters, however, failed to show any abnormalities in the patient group. The only abnormal finding in Parkinsonian subjects was an increased resistance to passive stretch under static conditions, presumably elastic in origin. The results are evidence against a contribution of altered contractile properties to muscular rigidity in Parkinsonism.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Locomotion in Parkinson's disease: neuronal coupling of upper and lower limbs.

Quadrupedal limb coordination during human walking was recently shown to be upregulated during obstacle stepping. An anticipatory activity of coupled cervico-thoraco-lumbar interneuronal circuits is followed by an appropriate executory activation of leg and arm muscles during task performance. This mechanism was studied in subjects with Parkinson's disease and age-matched controls walking on a ...

متن کامل

Magnetic Resonance Assessment of Hypertrophic and Pseudo-Hypertrophic Changes in Lower Leg Muscles of Boys with Duchenne Muscular Dystrophy and Their Relationship to Functional Measurements

INTRODUCTION The primary objectives of this study were to evaluate contractile and non-contractile content of lower leg muscles of boys with Duchenne muscular dystrophy (DMD) and determine the relationships between non-contractile content and functional abilities. METHODS Lower leg muscles of thirty-two boys with DMD and sixteen age matched unaffected controls were imaged. Non-contractile con...

متن کامل

The effect of circuit resistance training on body composition and physical function in patients with Parkinson's disease

Introduction: Parkinson's disease is the second age-related neurodegenerative disease that is clinically characterized by motor and non-motor symptoms. The aim of this study was to determine the effect of circuit resistance training on motor neuromuscular function in patients with Parkinson's disease. Materials and Methods: In this semi-experimental research, 20 patients with Parkinson's di...

متن کامل

LATE ARTERIAL REPAIR FOR LOWER LIMB OR KNEE SALVAGE

The objective of this report is to prove that even after development of ischemic necrosis of the muscles and nerves, we can still save the extremity or the knee and even several days after arterial injury, perform arterial repair and other mentioned procedures. Thus we can retain a functionally satisfactory leg or knee joint, which is far better than classic above-knee amputation and utili...

متن کامل

Passive mechanical properties of gastrocnemius in people with multiple sclerosis.

BACKGROUND There is evidence to suggest that contractile properties of muscles in people with multiple sclerosis change as a consequence of demyelination in central nervous system. However, passive properties of muscles in people with multiple sclerosis have not been previously investigated. The purpose of this study was to characterise passive mechanical properties of gastrocnemius in people w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره 54 5  شماره 

صفحات  -

تاریخ انتشار 1991